Table 1.
The accuracy of gene fusion detection on the simulated datasets.
| FusionSeeker | JAFFAL | LongGF | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Recall | Precision | F1 score | Recall | Precision | F1 score | Recall | Precision | F1 score | |
| Iso-Seq | |||||||||
| Exonic | 96.00 | 96.88 | 96.32 | 69.33 | 96.57 | 80.72 | 96.00 | 97.03 | 96.51 |
| Intronic | 94.67 | 90.00 | 92.28 | 14.67 | 66.67 | 24.04 | 54.67 | 94.87 | 69.36 |
| Total | 95.56 | 93.89 | 94.71 | 51.11 | 82.73 | 63.15 | 82.22 | 96.14 | 88.58 |
| Nanopore | |||||||||
| Exonic | 99.00 | 94.98 | 96.95 | 73.00 | 96.35 | 83.06 | 98.00 | 96.70 | 97.35 |
| Intronic | 99.33 | 78.72 | 87.84 | 18.00 | 53.81 | 26.98 | 56.67 | 91.80 | 70.08 |
| Total | 99.11 | 87.65 | 93.03 | 54.67 | 82.23 | 65.62 | 84.22 | 95.26 | 89.36 |
Note: Recall, precision, and F1 score in the table are the mean values of three replicate simulation datasets. Highest recall, precision, and F1 score among the three fusion callers are marked as bold.