Table 2.
Detection of previously validated gene fusions in cancer cell lines.
| FusionSeeker | JAFFAL | LongGF | |||||
|---|---|---|---|---|---|---|---|
| Cell line | Data type | Reported | Previously validate | Reported | Previously validate | Reported | Previously validated |
| SKBR3 | |||||||
| Iso-Seq | 30 | 15 | 25 | 13 | 16 | 10 | |
| MCF7 | |||||||
| Iso-Seq | 172 | 21 | 184 | 23 | 285 | 20 | |
| Nanopore | 61 | 20 | 34 | 18 | 41 | 20 | |
| HCT116 | |||||||
| Iso-Seq | 3 | 1 | 2 | 1 | 2 | 1 | |
| Nanopore | 17 | 1 | 12 | 1 | 10 | 1 | |
Note: Reported, number of gene fusions reported by each fusion caller. Previously validated, number of previously validated gene fusions detected by each fusion caller. Bold, the highest number of previously validated gene fusions reported among the three tools.