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. 2023 Jan 4;18(1):e0266985. doi: 10.1371/journal.pone.0266985

Table 3. Proportion and associated risk ratio of complication classes for the young compared to old adult with ARDS.

Complications ARDS (ages 18–49) ARDS (ages > 49) Risk Ratio with CI (95%) p-value
n = 1001 n = 6378
n (%) n (%)
Acute kidney failure 403 (40.3) 3431 (53.8) 0.8 [0.7; 0.9] <0.001
Cardiac arrest 57 (5.7) 455 (7.1) 1.1 [0.8; 1.5] 0.691
Cardiac complication 255 (25.5) 2195 (34.4) 0.8 [0.6; 0.9] 0.01
Cardiac Rhythm/conduction disorder 310 (31) 2847 (44.6) 0.6 [0.5; 0.7] <0.001
Digestive complication 393 (39.3) 2643 (41.4) 1 [0.9; 1.1] 0.907
Disorders of fluid, electrolyte and acid-base balance 546 (54.5) 3730 (58.5) 0.9 [0.9; 1] 0.02
Haematological disorder 388 (38.8) 2440 (38.3) 1 [0.9; 1] 0.528
Hemodynamic disorder 271 (27.1) 1852 (29) 1 [0.8; 1.1] 0.573
Arterial embolism and thrombosis 14 (1.4) 100 (1.6) 1.1 [0.6; 1.9] 0.737
Stroke 25 (2.5) 509 (8) 0.4 [0.2; 0.5] <0.001
Phlebitis and thrombophlebitis 180 (18) 777 (12.2) 1.3 [1; 1.6] 0.078
Pulmonary embolism 105 (10.5) 695 (10.9) 1 [0.8; 1.2] 0.637
Respiratory complication (excluding ARDS) 857 (85.6) 5502 (86.3) 1 [0.9; 1] 0.202
Pressure ulcer 115 (11.5) 818 (12.8) 1 [0.8; 1.2] 0.875
Viral reactivation 29 (2.9) 177 (2.8) 1.2 [0.8; 1.8] 0.356
Infections
 Aspergillosis 26 (2.6) 164 (2.6) 0.7 [0.5; 1.2] 0.179
 Candidiasis 64 (6.4) 421 (6.6) 1.2 [0.9; 1.5] 0.182
 Other fungal infection 21 (2.1) 111 (1.7) 1.1 [0.6; 1.9] 0.768
 Bacterial infection 528 (52.7) 3366 (52.8) 0.9 [0.9; 1] 0.187
 Bacterial intestinal infection 41 (4.1) 242 (3.8) 1.2 [0.9; 1.6] 0.299
 Respiratory bacterial superinfection 538 (53.7) 3507 (55) 1 [0.9; 1.1] 0.869
 Pneumonia due to Streptococcus pneumoniae 34 (3.4) 107 (1.7) 1.8 [1.2; 2.7] 0.009
 Streptococcal sepsis 41 (4.1) 145 (2.3) 1.6 [1.1; 2.3] 0.018