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Predicted amino acid sequences of Qo1 and Qo2 domains encoded by the Cyto b gene from the published T. annulata / C9 genome sequence and different T. annulata isolates with treatment failure history. Putative Qo1 and Qo2 domains are located between 116–144 and 238–273 amino acids of the protein around the ubiquinone binding site. Predicted amino acid substitutions associated with buparvaquone resistance are marked with ◊.
