Table 4. IC50 values of A10/BT and A21/AT1 clones with substitutions V135A and P253S.
V135A | P253S | |||
---|---|---|---|---|
Clone code | IC50 value (ng/mL) |
Clone code | IC50 value (ng/mL) |
|
Clones with mutation |
A10/BT/clone-1 |
65.34 |
A21/AT1/clone-13 |
6.36 |
A10/BT/clone-2 | 57.90 | A21/AT1/clone-15 | 37.70 | |
A10/BT/clone-3 |
12.62 | A21/AT1/clone-17 | 18.95 | |
Clones without mutation |
A10/BT/clone-7 | 0.73 | A21/AT1/clone-14 | 1.97 |
A10/BT/clone-13 | 1.51 | A21/AT1/clone-24 | 1.55 | |
A10/BT/clone-21 | 1.33 | A21/AT1/clone-25 | 3.17 |