Figure 5.

KEGG enrichment of differential metabolites. The abscissa is the ratio of the number of differential metabolites in the corresponding metabolic pathway to the total number of metabolites identified in the pathway. The larger the value, the higher the enrichment of differential metabolites in the pathway. The color of the dot represents the P-value of the hypergeometric test. The smaller the value, the greater the reliability of the test and the more statistically significant it is. The size of the dot represents the number of different metabolites in the corresponding pathway. The larger the dot, the more differential metabolites were found in the pathway. The most significant differential metabolites in the KEGG pathway in the R0 vs S0 group (A), R1 vs S1 group (B), and R6 vs S6 group (C).