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. 2022 Dec 8;3:1012463. doi: 10.3389/fgwh.2022.1012463

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© 2022 Jamu and Okamoto.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Relative hormone level during the four estrus phases. Cycling of oestrogen levels during the menstrual cycle was compared to the expression of HTR2A and HTR1A encoding 5-HT2a and 5-HT1a receptors, respectively. Oestrogen receptor (ER) also regulates TPH1 encoding one of the serotonin biosynthesis genes. Created with BioRender.com.