Table 1.
Serotonin receptor expression in sex organs. GPCR 5-HT receptors expressed in female and Male organs according to Human Protein Atlas (13).
| GPCR serotonin receptor | Female organs | Male organs |
|---|---|---|
| 5-HT1a | Ovary, breasts | Testis, seminal vesicle |
| 5-HT1b | Placenta, vagina, breasts, cervix, endometrium, fallopian tube, ovary | Testis, seminal vesicle, prostate |
| 5-HT1d | Fallopian tube, endometrium, breasts, placenta | Testis, prostate, seminal vesicle |
| 5-HT1e | Placenta, vagina, breasts, cervix, endometrium, fallopian tube, ovary | Testis, epididymis, prostate, seminal vesicle |
| 5-HT1f | Placenta, vagina, breasts, cervix, endometrium, fallopian tube, ovary | Testis, epididymis, prostate, seminal vesicle |
| 5-HT2a | Vagina, breasts, cervix, endometrium, fallopian tube, ovary | Testis, prostate, seminal vesicle |
| 5-HT2b | Placenta, vagina, breasts, cervix, endometrium, fallopian tube, ovary | Testis, prostate, seminal vesicle |
| 5-HT2c | None reported | None reported |
| 5-HT4 | Cervix, endometrium, fallopian tube | None reported |
| 5-HT5a | Breast, endometrium, fallopian tube, placenta | Testis, epididymis, seminal vesicle |
| 5-HT5b | Pseudogene | Pseudogene |
| 5-HT6 | None reported | Testis |
| 5-HT7 | Vagina, breasts, cervix, endometrium, fallopian tube, ovary | Testis, epididymis, prostate, seminal vesicle |