Skip to main content
. 2022 Dec 21;9:1032771. doi: 10.3389/fnut.2022.1032771

TABLE 3.

General observations of medium-term carcinogenicity test on rats for 15 weeks.

Group Chemical Treatment Body weight (g) Consumption (/rat/day)
Initial Final Food (g) Water (ml)
1 DEN 5% Tween 80 92 ± 6.3 401 ± 46.1* 17 ± 4.5* 24 ± 7.6*
2 DEN CRE 100 mg/kg BW 92 ± 6.8 407 ± 39.4 19 ± 3.5 25 ± 11.3
3 DEN CRE 500 mg/kg BW 93 ± 7.4 421 ± 28.6 20 ± 4.4 28 ± 9.6
4 DEN RRE 100 mg/kg BW 92 ± 4.2 401 ± 23.4 18 ± 4.3 23 ± 8.6
5 DEN RRE 500 mg/kg BW 92 ± 7.8 395 ± 28.0 20 ± 3.7 24 ± 6.8
6 DEN VA 75 mg/kg BW 93 ± 8.7 441 ± 24.6 22 ± 4.9 28 ± 7.6
7 NSS 5% Tween 80 93 ± 13.3 467 ± 48.9 23 ± 6.0 31 ± 4.7
8 NSS CRE 500 mg/kg BW 93 ± 4.2 457 ± 15.7 23 ± 4.8 30 ± 5.8
9 NSS RRE 500 mg/kg BW 93 ± 4.1 453 ± 38.8 23 ± 5.3 29 ± 4.0

Values are expressed as mean ± SD.

*Significantly different from the negative control (group 7), p < 0.05.

CRE, cooked glutinous purple rice extract; RRE, raw glutinous purple rice extract; VA, vanillic acid; DEN, diethylnitrosamine; NSS, normal saline solution.