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. 2022 Dec 21;14:1087238. doi: 10.3389/fnsyn.2022.1087238

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Copyright © 2022 Boxer and Aoto.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Neurexin structure. Nrxns are encoded from three genes (Nrxns 1–3). α-Nrxns (1–3) contain 6 LNS domains, 3 EGF-like-repeats, and up to 6 sites of alternative splicing. β-Nrxns (1–3) contain LNS6 and splice sites 4 and 5. γ-Nrxn (Nrxn1 only) is highly truncated. Reproduced with permission from Boxer et al. (2021).