Table 4.
Fasting BGL (mg/dl) | % of BGL reduction | ||||
---|---|---|---|---|---|
Dose | Day 0 | Day 7 | Day 14 | 7th day | 14th day |
DNC | 281.01 ± 1.25 | 278.67 ± 2.35 | 276.72 ± 1.25 | 0.83 | 1.53 |
GCL 5 mg/kg | 279.78 ± 2.7 | 216.89 ± 2.96β3a3b3 | 194.61 ± 2.86β3a3b3c3 | 22.49 | 30.44 |
CE100 mg/kg | 278.84 ± 2.33 | 254.15 ± 1.43 | 250.05 ± 1.11 | 8.85 | 10.32 |
CE200 mg/kg | 277.35 ± 2.86 | 237.16 ± 1.57β3a2b2 | 212.02 ± 2.05β3a3b3 | 14.49 | 23.56 |
CE400 mg/kg | 280.67 ± 1.97 | 221.93 ± 1.83β3a3b3 | 198.21 ± 3.36β3a3b3c2 | 20.93 | 29.38 |
NNC | 94.43 ± 0.98 | 92.49 ± 1.77 | 89.76 ± 2.25 | 2.05 | 4.94 |
Each value represents mean ± SEM; n = 6 for each treatment,. βCompared to day zero (baseline blood glucose level); acompared to diabetes control; bcompared to 100 mg/kg, ccompared to 200 mg/kg, 1p < 0.05, 2p < 0.01, and 3p < 0.001. BGL = blood glucose level, CE = crude extract, DNC = diabetes negative control received 10 ml/kg 2% tween 80 in distilled water GLC = glibenclamide, NNC = normal negative control received 10 ml/kg 2% tween 80 in distilled water.