Table 5.

The effect of repeated daily dose of the crude extract on the serum lipid level of diabetic mice.

Serum lipid level (mg/dl)
Dose	TC	TG	LDL-C	VLDL-C	HDL-C
DNC	192.41 ± 1.60b3	155.69 ± 2.84	102.33 ± 3.34b3	35.26 ± 1.49b3	25.73 ± 1.82
GCL 5 mg/kg	118.12 ± 4.14a3	83.59 ± 1.92a3	48.77 ± 1.07a3	21.13 ± 1.01a3	44.65 ± 1.31a3
CE100 mg/kg	168.17 ± 3.92b3	149.62 ± 3.11b3	90.37 ± 2.38b3	38.03 ± 0.41b3	30.67 ± 1.54b3
CE200 mg/kg	128.17 ± 1.18a3	89.31 ± 3.18a3	51.53 ± 1.56a3	25.68 ± 0.57a2	36.31 ± 1.02a3
CE 400 mg/kg	121.04 ± 0.69a3	86.59 ± 1.54a3	48.73 ± 1.53a3	23.51 ± 0.62a3	39.58 ± 0.57a3
NNC	115.43 ± 3.25a3	78.75 ± 2.33a3	41.08 ± 1.05a3	19.93 ± 0.42a3	45.35 ± 1.23a3

Each value represents mean ± SEM (n = 6 mice in each group) and analyzed by one-way ANOVA followed by Post Hoc Tukey's test; ^acompared to the diabetic control, ^bcompared to the normal control; ^1p < 0.05, ^2p < 0.01, and ^3p < 0.001. TC = Total cholesterol, TG = triacylglycerol (TG), VLDL-C = verylow-density lipoprotein cholesterol, LDL-C = low-density lipoprotein cholesterol, HDL-C = high-density lipoprotein cholesterol, CE = crude extract, DNC = diabetes negative control that received 10 ml/kg 2% tween 80 in distilled water GLC = glibenclamide, NNC = normal negative control that received 10 ml/kg 2% tween 80 in distilled water.