Fig. 5.

High expression of nerve growth factor (NGF) reverses the inhibition of SST0001 on the malignant phenotype of melanoma cells. (A) Cell viability was measured by MTT assay in B16-F10 cells. (B) The proliferation of melanoma cells was detected by the EdU detection kit (200×, scale bar = 100 μm). (C) Transwell assay was used to determine cell migration and invasion (200×, scale bar = 200 μm). *P < 0.05, **P < 0.01 versus control. ^#P < 0.05, ^##P < 0.01 versus SST0001. The error bars indicate mean ± standard deviation. MTT: 3-[4,5-dimethyl-2-thiazolyl]-2,5 diphenyl-2H-tetrazolium bromide, EdU: 5-Ethynyl-20-deoxyuridine.