Fig. 4.
(a) Confocal images of Hepa1-6 cells after incubated with DiO-modified PD1-CM or CHO-CM. Scale bar: 20 μm; (b) confocal images of Hepa1-6 cells and anti-PD-L1 antibody pre-treated Hepa1-6 cells after incubated with DiO-modified MnO2@PD1-CM, Scale bars: 20 μm; (c) DCFH-DA indicating the production of intracellular ROS in Hepa1-6 cells after treated with PD1-CM, MnO2 or MnO2@PD1-CM; cell viability of Hepa1-6 cells after treated with different concentrations of MnO2 (d) or MnO2@PD1-CM (e) for 24 h.
