Table 5.
SARS-CoV-2 infection severity according to anti-SARS-CoV-2 IgG reactive antibody cut-off before the occurrence of SARS-CoV-2 infection in evaluable patients.
| Variable | <250 BAU/mL At 3–6 weeks (n = 504) | ≥250 BAU/mL At 3–6 weeks (n = 746) | P value | <250 BAU/mL At 3 months (n = 430) | ≥250 BAU/mL At 3 months (n = 480) | P value | <250 BAU/mL At 6 months (n = 300) | ≥250 BAU/mL At 6 months (n = 541) | P value |
|---|---|---|---|---|---|---|---|---|---|
| SARS-CoV-2 infection | 119 (23.6%) | 110 (14.7) | <0.001 | 86 (20%) | 50 (10%) | <0.001 | 67 (22%) | 77 (14%) | 0.004 |
| Symptomatic SARS-CoV-2 | 77/119 (65%) | 45/110 (41%) | <0.001 | 56/86 (65%) | 18/50 (36%) | 0.001 | 43/67 (64%) | 28/77 (36%) | 0.001 |
| Pneumonia | 38/119 (32%) | 7/110 (6%) | <0.001 | 21/86 (24%) | 1/50 (2%) | <0.001 | 13/67 (19%) | 3/77 (3.8%) | 0.004 |
| Hospital admission | 38/119 (32%) | 6/110 (5%) | <0.001 | 22/86 (25.5%) | 0 | <0.001 | 16/67 (23.8%) | 3/77 (3.8%) | <0.001 |
| Oxygen requirement | 31/119 (33%) | 3/110 (2.7%) | <0.001 | 19/86 (22%) | 0 | <0.001 | 13/67 (19%) | 1/77 (1.2%) | <0.001 |
| ICU admission | 4/119 (3.8%) | 1/110 (0.9%) | 0.3 | 1/86 (1.2%) | 0 | 0.9 | 0 | 1/77 (1.2%) | 0.9 |
| Death | 5/119 (4.2%) | 0 | 0.06 | 2/86 (2.4%) | 0 | 0.5 | 3/67 (4.5%) | 0 | 0.09 |