Skip to main content
. 2023 Jan 1;20(1):23–34. doi: 10.7150/ijms.68778

Figure 2.

Figure 2

RPPH1 regulates HCC cell proliferation and apoptosis. (A) The expression of RPPH1 in HCC cells was measured by qRT-PCR following transfection with RPPH1 or shRPPH1. (B, C) MTS and EdU assays showed that RPPH1 promoted the growth of Huh7 cells, while shRPPH1 repressed the growth of HCCLM9 cells. (D) Colony formation assays showed that colony-forming efficiency was increased by RPPH1 and decreased by shRPPH1. (E, F) Flow cytometry and TUNEL staining showed that RPPH1 reduced, and shRPPH1 induced the apoptosis of HCC cells. Data are presented as the mean ± SD. *p < 0.05, ** p < 0.01, ***p < 0.001, ****p < 0.0001.