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. 2022 Dec 5;17(1):173–187. doi: 10.1002/1878-0261.13345

Fig. 5.

Fig. 5

Mediation analysis for trans‐omics regulatory pathway. VanderWeele causal mediation analysis was conducted to evaluate the indirect effect, 95% CI, and P value of epigenetic G × G interactions on overall survival of NSCLC patients via transcriptional G × G interactions.