Table 1.
Demographic and clinical characteristics of patients with schizophrenia and healthy controls
| Schizophrenia patients |
Comparision |
|||||||
|---|---|---|---|---|---|---|---|---|
| Healthy Controls (n=83) | Treatment Initiation (n=45) | Treatment Responsive (n=40) | Treatment Resistant (n=42) | Four groups | Treatment Resistant Versus Treatment Responsive | |||
|
| ||||||||
| mean ± s.d. | mean ± s.d. | mean ± s.d. | mean ± s.d. | F/χ2 | p | T/χ2 | p | |
| Demographic information | ||||||||
| Sex(M/F) | 44/39 | 18/27 | 26/14 | 29/13 | 5.8 | 0.12 | 0.15 | 0.82 |
| Age (years) | 38.6 ± 12.2 | 29.6 ± 10.0 | 46.4 ± 11.1 | 47.7 ± 9.1 | 25.1 | 7.3×10−14 | −0.6 | 0.55 |
| Age range | 19~59 | 15~54 | 21~60 | 25~62 | ||||
| Education (years) | 13.1 ± 2.6 | 12.4 ± 3.6 | 12.1 ± 3.1 | 12.1 ± 2.9 | 1.8 | 0.16 | −0.1 | 0.91 |
| Illness duration (years) | 1.1±1.2 | 22.2±12.9 | 23.6±10.2 | −0.5 | 0.59 | |||
| Onset age | 28.2±9.8 | 24.0±5.8 | 22.6±5.9 | 1.1 | 0.27 | |||
| Symptoms | ||||||||
| PANSS positive | 21.9 ± 5.5 | 10.9± 4.0 | 23.4 ± 4.4 | −13.5 | 1.6×10−22 | |||
| PANSS negative | 14.8 ± 5.5 | 14.5 ± 5.8 | 24. 0 ± 7.3 | −6.5 | 2.3×10−10 | |||
| PANSS total | 74.1 ± 13.6 | 49.4 ± 10.7 | 86.2 ± 12.6 | −14.2 | 8.5×10−26 | |||
| Antipsychotic dosage (chlorpromazine equivalents) | 306.6 ± 183.2 | 447.8 ± 220.1 | 733.8 ± 231.1 | −5.7 | 1.69×10−7 | |||
Note: PANSS=Positive and Negative Syndrome Scale