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. Author manuscript; available in PMC: 2023 Jan 5.
Published in final edited form as: Acta Neuropathol. 2022 Oct 20;145(1):127–143. doi: 10.1007/s00401-022-02510-8

Figure 5:

Figure 5:

A) Lysates from skeletal muscle and tissues indicated from DNAJB4 homozygous knockout mice or control littermates immunoblotted with an antibody to DNAJB4 or GAPDH. B) X-ray image highlighting the skeleton of 8 month old DNAJB4 knockout (B4KO) or C57 control. C) Quantitation of the kyphotic index from 4 and 8 month old control or DNAJB4 knockout (B4KO) mice. D) Mean holding impulse on an inverted screen for 4 and 8 month old C57 control and DNAJB4 KO mice. E) Peak force forelimb grip strength testing for 4- and 8-month-old C57 control and DNAJB4 KO mice. F-G) Weight of indicated isolated muscles (tibialis anterior (TA), gastrocnemius (Gast) and quadriceps (Quad)) normalized to total body weight for 4- and 8-monthold C57 control and DNAJB4 KO mice.