Table 2.
Two-way repeated measures ANOVA used to analyze effects of post-session mAChR blockade on different measures of the operant discrimination task.
| Variable | Training stage | Effect | F value | p value | Post hoc analysis |
|---|---|---|---|---|---|
| Rewards | Tone training | Day | 6.38 | 1.39 × 10−4 | No sig. differences between scop and saline groups |
| Drug | 0.025 | 0.88 | |||
| Day by Drug | 4.40 | 7.00 × 10−3 | |||
| Discrimination training | Day | 63.30 | 2.24 × 10−19 | Saline is sig. different from scop on days 11, 12, 14–16 (p < 0.05) | |
| Drug | 9.94 | 4.60 × 10−3 | |||
| Day by Drug | 5.72 | 2.00 × 10−3 | |||
| Incorrect NPs | Tone training | Day | 6.68 | 9.87 × 10−4 | No sig. differences between scop and saline groups |
| Drug | 0.21 | 0.65 | |||
| Day by Drug | 1.81 | 0.15 | |||
| Discrimination training | Day | 61.57 | 2.46 × 10−26 | Saline is sig. different from scop on days 15 and 17 (p < 0.05) | |
| Drug | 0.28 | 0.60 | |||
| Day by Drug | 5.69 | 2.74 × 10−4 | |||
| Inactive NPs | Tone training | Day | 14.68 | 1.20 × 10−5 | No sig. differences between scop and saline groups |
| Drug | 0.27 | 0.61 | |||
| Day by Drug | 0.14 | 0.90 | |||
| Discrimination training | Day | 5.25 | 5.83 × 10−4 | No sig. differences between scop and saline groups | |
| Drug | 0.22 | 0.65 | |||
| Day by Drug | 1.27 | 0.28 | |||
| Tones | Tone training | Day | 1.45 | 0.24 | No sig. differences between scop and saline groups |
| Drug | 0.42 | 0.52 | |||
| Day by Drug | 1.22 | 0.31 | |||
| Discrimination training | Day | 22.91 | 2.13 × 10−14 | Saline is sig. different from scop on days 15–17 (p < 0.05) | |
| Drug | 5.49 | 0.03 | |||
| Day by Drug | 5.65 | 2.14 × 10−4 | |||
| Hit rate | Tone training | Day | 5.95 | 2.35 × 10−3 | No sig. differences between scop and saline groups |
| Drug | 0.04 | 0.85 | |||
| Day by Drug | 4.98 | 3.50 × 10−3 | |||
| Discrimination training | Day | 40.32 | 2.24 × 10−22 | No sig. differences between scop and saline groups | |
| Drug | 7.58 | 0.01 | |||
| Day by Drug | 1.71 | 0.04 | |||
| Receptacle Entries | Tone training | Day | 6.74 | 2.10 × 10−3 | No sig. differences between scop and saline groups |
| Drug | 1.60 | 0.22 | |||
| Day by Drug | 0.77 | 0.52 | |||
| Discrimination training | Day | 9.73 | 2.55 × 10−21 | No sig. differences between scop and saline groups | |
| Drug | 1.34 | 0.26 | |||
| Day by Drug | 0.46 | 0.97 |