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. 2022 Jul 15;44(1):234–243. doi: 10.1038/s41401-022-00949-9

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© The Author(s), under exclusive licence to Shanghai Institute of Materia Medica, Chinese Academy of Sciences and Chinese Pharmacological Society 2022, corrected publication 2023. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.

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Fig. 6 — a A plot of IRE1α RNase IC₅₀ as a function of ROS production induced by TXF and its derivatives (0.5 μM) or b the binding energies docking TXF and its derivatives to IRE1α and a, b their correlation analysis.