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. 2022 Nov 22;36(1):209–222. doi: 10.1007/s13577-022-00820-3

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Fig. 5 — TRIM59 could interact with GPX4 and promote its ubiquitination. A, B The protein (A) and mRNA (B) levels of GPX4 in L02 cells transduced with shTRIM59 adenovirus or oeTRIM59 lentivirus. C Co-IP assay of the interaction between TRIM59 and GPX4. D The expression of GPX4 in L02 cells transduced with oeTRIM59 or vector and treated with 20 mM cycloheximide (CHX). E The expression of GPX4 in L02 cells transduced with oeTRIM59 or vector and treated with 10 μM MG132 or DMSO for 20 h. F The ubiquitination level of GPX4 in L02 cells transduced with oeTRIM59 or vector