Table 2.
Latent class results | |||||||
---|---|---|---|---|---|---|---|
Attributes | Class 1: find my cancer (43%) | Class 2: sensitivity/specificity trade-off (41%) | Class 3: wary of screening; particularly false results (16%) | ||||
MLE (SE) | 95% CI | MLE (SE) | 95% CI | MLE (SE) | 95% CI | ||
1. Preferences | |||||||
Alternative specific constant | Screening A | Reference | – | Reference | – | Reference | – |
Screening B | 0.1123 (0.0729) | [− 0.0306; 0.2552] | − 0.0152 (0.0328) | [− 0.0796; 0.0491] | −0.1025 (0.0767) | [− 0.2529; 0.0479] | |
No screening | − 3.3865 (0.2871)*** | [− 3.9492; − 2.8239] | − 2.8686 (0.1631)*** | [− 3.1883; − 2.5489] | 0.0071 (0.1591) | [− 0.3047; 0.3190] | |
Number of cancers tested for | 1-Type increase | 0.0205 (0.0026)*** | [0.0153; 0.0257] | 0.0034 (0.0014)* | [0.0007; 0.0061] | 0.0002 (0.0022) | [−0.0040; 0.0045] |
True positives | 1-Case increase | 0.0484 (0.0045)*** | [0.0397; 0.0571] | 0.0076 (0.0014)*** | [0.0048; 0.0103] | 0.0131 (0.0018)*** | [0.0096; 0.0165] |
False negatives | 1-Case decrease | 0.0631 (0.0053)*** | [0.0527; 0.0736] | 0.0065 (0.0018)*** | [0.0030; 0.0099] | 0.0363 (0.0027)*** | [0.0310; 0.0416] |
False positives | 10-People decrease | 0.0085 (0.0007)*** | [0.0070; 0.0100] | 0.0046 (0.0004)*** | [0.0039; 0.0053] | 0.0078 (0.0009)*** | [0.0061; 0.0095] |
Cancer type unknown | 1% Decrease | − 0.0636 (0.0112)*** | [− 0.0856; − 0.0416] | 0.0163 (0.0057)** | [0.0051; 0.0276] | 0.0258 (0.0096)** | [0.0069; 0.0447] |
2. Class membership | |||||||
Constant | – | Reference | – | 0.0128 (0.0619) | [− 0.1085; 0.1341] | − 0.9672 (0.0425)*** | [− 1.0505; − 0.8839] |
Analysis information: respondents = 1700; observations = 13,600; parameters = 23; LL = − 9807.2; BIC = 19833.3; APR = 34.21%
APR adjusted McFadden Pseudo-R2, BIC Bayesian information criteria, CI confidence interval, LL Log-likelihood, MLE maximum likelihood estimate, SE standard error, *p < 0.05; **p < 0.01; ***p < 0.001