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. 2022 Jul 18;16(1):43–56. doi: 10.1007/s40271-022-00589-5

Table 2.

Preferences by latent class

Latent class results
Attributes Class 1: find my cancer (43%) Class 2: sensitivity/specificity trade-off (41%) Class 3: wary of screening; particularly false results (16%)
MLE (SE) 95% CI MLE (SE) 95% CI MLE (SE) 95% CI
1. Preferences
 Alternative specific constant Screening A Reference Reference Reference
Screening B 0.1123 (0.0729) [− 0.0306; 0.2552] − 0.0152 (0.0328) [− 0.0796; 0.0491] −0.1025 (0.0767) [− 0.2529; 0.0479]
No screening − 3.3865 (0.2871)*** [− 3.9492; − 2.8239] − 2.8686 (0.1631)*** [− 3.1883; − 2.5489] 0.0071 (0.1591) [− 0.3047; 0.3190]
 Number of cancers tested for 1-Type increase 0.0205 (0.0026)*** [0.0153; 0.0257] 0.0034 (0.0014)* [0.0007; 0.0061] 0.0002 (0.0022) [−0.0040; 0.0045]
 True positives 1-Case increase 0.0484 (0.0045)*** [0.0397; 0.0571] 0.0076 (0.0014)*** [0.0048; 0.0103] 0.0131 (0.0018)*** [0.0096; 0.0165]
 False negatives 1-Case decrease 0.0631 (0.0053)*** [0.0527; 0.0736] 0.0065 (0.0018)*** [0.0030; 0.0099] 0.0363 (0.0027)*** [0.0310; 0.0416]
 False positives 10-People decrease 0.0085 (0.0007)*** [0.0070; 0.0100] 0.0046 (0.0004)*** [0.0039; 0.0053] 0.0078 (0.0009)*** [0.0061; 0.0095]
 Cancer type unknown 1% Decrease − 0.0636 (0.0112)*** [− 0.0856; − 0.0416] 0.0163 (0.0057)** [0.0051; 0.0276] 0.0258 (0.0096)** [0.0069; 0.0447]
2. Class membership
 Constant Reference 0.0128 (0.0619) [− 0.1085; 0.1341] − 0.9672 (0.0425)*** [− 1.0505; − 0.8839]

Analysis information: respondents = 1700; observations = 13,600; parameters = 23; LL = − 9807.2; BIC = 19833.3; APR = 34.21%

APR adjusted McFadden Pseudo-R2, BIC Bayesian information criteria, CI confidence interval, LL Log-likelihood, MLE maximum likelihood estimate, SE standard error, *p < 0.05; **p < 0.01; ***p < 0.001