This study quantified how individuals aged 50–80 years in the USA value multi-cancer early detection screening tests.

In an online discrete choice experiment, three groups were identified who valued multi-cancer early detection differently and named as follows by the researchers: find my cancer (43%), sensitivity/specificity trade-off (41%), wary of screening: particularly false results (16%).

Overall, accuracy (fewer false negatives and false positives, more true positives) was of greatest importance.

72% of participants would opt for multi-cancer early detection screening in addition to recommended cancer screenings.

Multi-cancer early detection screening tests are likely to be of high value to the majority of this population.