Table 2.

Summary of treatment-emergent adverse events (TEAEs)

n (%)	90 mg/day (n = 4)	120 mg/day (n = 6)	160 mg/day (n = 4)	Total (n = 14)
TEAE	4 (100.0)	5 (83.3)	4 (100.0)	13 (92.9)
Serious TEAE	2 (50.0)	2 (33.3)	0 (0.0)	4 (28.6)
TEAE by CTCAE grade
≤ 2	0 (0.0)	3 (50.0)	0 (0.0)	3 (21.4)
≥ 3	4 (100.0)	2 (33.3)	4 (100.0)	10 (71.4)

Treatment-emergent adverse event (TEAE) is an adverse event that occurs after the first administration or worsens relative to the pretreatment state

Coded with Medical Dictionary for Regulatory Activities (MedDRA) Version 21.1