Table 2.
Comparison of demographics of psychopharmacologically treated patients with and without a serious adverse drug reaction (sADR)
| Patients treated in the therapy ward and/or ICU | CAMD treated in the specialized clinic | |||
|---|---|---|---|---|
| Patients with sADR | Patients without sADR | Patients with sADR | Patients without sADR | |
| N (%) | 30 (5.8) | 513 | 23 (20.0) | 92 |
| Sex | ||||
| Male, n (%) | 13 (43) | 227 (44) | 12 (52) | 65 (71) |
| Female, n (%) | 17 (57) | 286 (56) | 11 (48) | 27 (29) |
| Age (SD, Range) (Jahre) | 15.4 (1.6; 10–18) | 14.1 (2.7; 5–22) | 14,5 (3,0; 8–19) | 13,2 (3,5; 7–19) |
| Self-harming behavior, n (%) | 11 (36.7) | 211 (41.1) | 2 (8.7) | 2 (2.2) |
| Epilepsy, n (%) | 2 (6.7) | 11 (2.1) | 8 (34.8) | 16 (7.4) |
| Main diagnoses of mental disorders (ICD-10) | ||||
| Mental and behavioral disorders caused by psychotropic substances (F1), n (%) | 1 (3) | 4 (1) | – | – |
| Schizophrenia spectrum disorders (F2), n (%) | 9 (30) | 8 (2) | 3 (13) | 3 (3) |
| Affective disorders (F3), n (%) | 11 (37) | 189 (37) | – | 2 (2) |
| Neurotic, stress and somatoform disorders (F4), n (%) | 4 (13) | 85 (17) | 1 (4) | 3 (3) |
| Behavioral disorders with physical disorders and factors (F5), n (%) | 2 (7) | 16 (3) | – | 2 (2) |
| Personality and behavioral disorders (F6), n (%) | – | 21 (4) | 2 (8) | 1 (1) |
| Intelligence disorder (F7), n (%) | – | 3 (1) | 3 (13) | 1 (1) |
| Developmental disorders (F8), n (%) | 1 (3) | 13 (3) | 7 (30) | 42 (46) |
| Behavioral and emotional disorders with onset in childhood and adolescence (F9), n (%) | 2 (7) | 174 (34) | 7 (30) | 37 (40) |
| Total treatment duration (days) (SD, range) | 51.7 (51.3; 1–253) | 28.8 (33.1, 0–344) | 69.7 (53.7; 1–185) | 65.4 (37.9; 1–189 |
sADR serious adverse drug reaction, ICU intensive unit care, CAMD children and adolescents with multiple disabilities and mental disorders