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. 2023 Jan 4;14:51. doi: 10.1038/s41467-022-35658-8

Fig. 5. Similarity between cerebellar and cerebral feedback is task and learning-dependent.

Fig. 5

a Cerebro-cerebellar cosine similarity throughout task sequences that do not require intermediate external feedback: a simple line drawing with feedback only at the end of the task (LD end-only) and online visual discrimination (ns denotes not significant: simple LD visuomotor p = 0.212 (0%), p = 0.520 (25%); online LD visuomotor p = 0.312 (0%), p = 0.06 (25%), p = 0.067 (50%), p = 0.386 (60%). Here and in subsequent panels, red arrows indicate points in which external feedback is available. Cosine similarity throughout the tasks is calculated across all training sessions (see the “Methods” section). b Cerebro-cerebellar cosine similarity over learning for three-time points in the task: early (turquoise), mid (blue) and late (purple) in the task (cf. a). c Cerebro-cerebellar cosine similarity throughout the sequence for tasks with intermediate external feedback: simple line drawing (LD), online LD, online digitdrawing (DD). d Cerebro-cerebellar cosine similarity over learning for three different time points in the task (early, mid and late as in b). Dashed black line represents zero similarity. **p < 0.01, ***p < 0.001, ****p < 0.0001 (two-sided paired t-test between cosine similarity and zero). Error bars represent mean ± SEM across 10 different initial conditions (20 for the simple LD visuomotor end-only task). Source data are provided as a Source Data file.