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. 2022 Jul 1;44(1):1–7. doi: 10.1038/s41401-022-00938-y

Fig. 1. Comparison between predicted models and experimental structures with large ECD.

Fig. 1

Experimental structures and predicted models for glucagon-like peptide 1 receptor (GLP1R) (a), parathyroid hormone 2 receptor (PTH2R) (b), active (c) and inactive (d) luteinizing hormone and choriogonadotropin receptor (LHCGR) in different ways of alignments. Cryo-EM structures of GLP1R (PDB ID: 7KI0), PTH2R (PDB ID: 7F16), LHCGR (PDB IDs: 7FIG and 7FIJ) are selected for calculation. Pink (or cyan) and blue cartoons represent experimental structures and predicted models, respectively. Two conflicts between the predicted model of GLP1R and the peptide ligand from the experimental structure are highlighted in red circles.