Fig. 4. Recognition mechanism of GSDMB by IpaH7.8.
a Electrostatic surface representations of NTD-GSDMB; LRR is shown in cartoon representation. The LRR units are indicated by numbers. b Electrostatic surface representations of LRR domain. NTD-GSDMB is shown in cartoon representation. The secondary elements of GSDMB involved in the binding of IpaH7.8 are labeled. c–f Close-up views of interactions in the interface between NTD-GSDMB and LRR domain of IpaH7.8.