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. 2022 Jun 15;44(1):133–144. doi: 10.1038/s41401-022-00924-4

Fig. 7. Proposed mechanism for the suppression P450s activity caused by ER stress.

Fig. 7

ER stress regulated hepatic ER membrane fluidity and phospholipid composition and cyt c released from mitochondria to interact with cyt b5, which are important reasons in P450s regulation.