Table 4.
Laboratory parameters of COVID-19 patients with normal PA-aO2 and abnormal PA-aO2 in different time points after admission
| T0 (D0–D2) | T1 (D3–D5) | T2 (D6–D8) | T3 (D9–D11) | T4 (D12–D14) | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Normal PA-aO2 | Abnormal PA-aO2 | Normal PA-aO2 | Abnormal PA-aO2 | Normal PA-aO2 | Abnormal PA-aO2 | Normal PA-aO2 | Abnormal PA-aO2 | Normal PA-aO2 | Abnormal PA-aO2 | |
| WBC | 4.7 (3.3, 5.8) | 4.6 (3.7, 5.9) | 5.2 (3.8, 7.0) | 5.5 (4.1, 7.8) | 5.7 (4.5, 6.6) | 6.2 (4.6, 8.2) | 5.8 (4.8, 7.4)a | 6.5 (5.4, 9.0) | 6.3 (5.2, 7.8)a | 7.2 (6.1, 10.2) |
| HGB | 131 (120, 141) | 130 (119, 141) | 132 (118, 143) | 130 (119, 143) | 130 (118, 141) | 127 (115, 142) | 123 (113, 139) | 124 (114, 136) | 128 (115, 137) | 126 (114, 137) |
| PLT | 172 (143, 227) | 170 (139, 230) | 200 (152, 263) | 211 (147, 269) | 218 (178, 272) | 233 (180, 313) | 219 (174, 284)a | 263 (203, 312) | 227 (180, 279)a | 269 (204, 330) |
| Lys | 1.2 (0.9, 1.8) | 1.11 (0.8, 1.5) | 1.3 (0.9, 1.7)a | 1.1 (0.7, 1.6) | 1.37 (1.0, 1.8) | 1.2 (0.8, 1.7) | 1.4 (1.0, 1.7) | 1.4 (1.1, 1.8) | 1.5 (1.2, 1.8) | 1.4 (1.1, 1.9) |
| CRP | 7.7 (2.0, 22.1)a | 17.2 (6.8, 36.4) | 9.1 (4, 21.6)a | 17.6 (8.3, 37.0) | 5.8 (2.4, 12.7) | 8.4 (3.7, 21.7) | 3.8 (2.0, 7.4) | 5.5 (2.2, 11.6) | 3.1 (1.3, 5.5)a | 5.0 (2.1, 11.4) |
| ESR | 25 (11, 51)a | 42 (23, 72) | 43 (17, 69)a | 59 (33, 78) | 51 (23, 78)a | 66 (37, 89) | 53 (28, 77) | 74 (41, 85) | 43 (12, 77) | 55 (26, 88) |
| PT | 11.9 (11.2, 12.4) | 11.8 (11.2, 12.5) | 11.3 (10.9, 12.0) | 11.4 (10.8, 12.2) | 10.8 (10.4, 11.3) | 10.8 (10.5, 11.5) | 10.9 (10.3, 11.2) | 10.7 (10.3, 11.3) | 10.8 (10.5, 11.4) | 10.8 (10.3, 11.5) |
| APTT | 32.4 (29.9, 35.1) | 32.7 (30.7, 35.0) | 31.8 (23.0, 34.1) | 31.7 (29.7, 34.5) | 31.9 (30.0, 33.8) | 31.2 (28, 2.3) | 31.0 (27.6, 33.1) | 30.1 (27.2, 32.9) | 32.4 (28.8, 34.6) | 29.9 (26.4, 33.0) |
| Fib | 3.4 (2.7, 3.9)a | 3.7 (3.1, 4.5) | 3.6 (2.9, 4.1)a | 3.9 (3.2, 4.6) | 3.4 (2.8, 3.9) | 3.6 (3.0, 4.3) | 3.1 (2.7, 3.6) | 3.3 (2.8, 3.9) | 2.9 (2.5, 3.3) | 3.2 (2.7, 3.6) |
| D-D | 0.2 (0.1, 0.5) | 0.3 (0.1, 0.6) | 0.2 (0.1, 0.4) | 0.3 (0.1, 0.6) | 0.2 (0.1, 0.3)a | 0.2 (0.1, 0.6) | 0.1 (0.1, 0.5)a | 0.2 (0.1, 0.7) | 0.2 (0.1, 0.5) | 0.3 (0.1, 1.1) |
| ALT | 17.1 (13.1, 23.4)a | 20.0 (14.3, 28.4) | 17.1 (12.8, 24.2) | 19.3 (15.0, 26.7) | 18.2 (14.0, 34.0) | 22.4 (15.6, 34.8) | 27.1 (15.6, 49.5) | 27.7 (16.2, 44.4) | 25.4 (16.0, 48.2) | 30.0 (19.7, 63.1) |
| AST | 21.6 (17.9, 27.9) | 25.3 (21.4, 32.9) | 20.7 (17.1, 26.4) | 22.4 (17.5, 29.0) | 22.2 (17.6, 30.0) | 23.5 (18.1, 29.6) | 23.6 (16.8, 31.4) | 23.3 (18.6, 31.7) | 26 (18.6, 34.0) | 26.0 (20.0, 34.3) |
| Tbil | 10.1 (8.1, 14.5) | 11.5 (8.8, 16.4) | 12.1 (9.4, 22.3) | 14.2 (9.4, 20.0) | 9.6 (6.8, 12.3) | 10.8 (8.0, 14.0) | 9.0 (7.1, 12.2) | 9.3 (7.0, 12.9) | 8.4 (6.8, 12.9) | 10.3 (8.2, 14.0) |
| ALB | 38.7 (35.9, 42.3) | 38.1 (35.2, 40.5) | 39.2 (36.0, 42.4)a | 37.3 (33.7, 40.6) | 39.1 (36.2, 42.4)a | 37.5 (32.9, 40.9) | 38.9 (34.3, 42.5) | 37.7 (33.2, 41.5) | 41.5 (38.6, 44.6)a | 38.1 (33.7, 41.9) |
| Cr | 51.1 (40.0, 68.1) | 51.3 (41.3, 61.9) | 55.8 (42.8, 73.2) | 55.1 (43.3, 64.7) | 64.3 (48.0, 75.6)a | 50.4 (41.4, 62.4) | 53.3 (46.1, 65.5) | 57.1 (46.1, 70.8) | 56.9 (47.2, 75.6) | 54.1 (45.0, 63.7) |
| BUN | 4.2 (3.6, 5.1) | 4.4 (3.2, 5.5) | 4.5 (3.6, 5.3) | 5.0 (3.9, 6.6) | 4.8 (4.0, 5.9) | 4.9 (4.0, 6.5) | 5.1 (4.2, 60.4) | 5.4 (4.6, 6.5) | 5.4 (4.4, 6.3) | 5.3 (4.7, 6.7) |
WBC white blood cell, HGB hemoglobin, PLT platelet, Lys lymphocytes, CRP C-reactive protein, ESR erythrocyte sedimentation rate, PT prothrombin time, APTT activated partial thromboplastin time, Fib fibrinogen, D-D D dimer, ALT alanine aminotranspherase, AST aspartate aminotransferase, TBil total bilirubin, ALB albumin, Cr serum creatinine, BUN urea nitrogen
aDifference significant