Fig. 22.

Nanomaterials for chemotherapy of OS. A) The smart RGD–Bi₂S₃@MSN/DOX nanoplatform for OS real-time X-ray CT imaging and NIR-responsive photothermal therapy-chemotherapy. (i) Representative images of tumor bearing mice from different treatment groups [75]. The images reproduced with the permission from WILEY-VCH. B) Schematic illustration of the preparation of BSA-IrO₂@DOX and served as a versatile nanoplatform for mild hyperthermia-induced DOX release and synergistic chemo-photothermal therapy [257]. The image reproduced with the permission from Informa UK. C) Illustration depicts PDA-ALN/SN38-associated bone-targeted chemo-photothermal treatment of malignant bone tumor [258]. The image reproduced with the permission from Elsevier Ltd.