Skip to main content
. 2022 Dec 26;24:263–312. doi: 10.1016/j.bioactmat.2022.12.014

Fig. 8.

Fig. 8

Gold nanomaterials for biomarkers detection in human biofluids. A) The preparation method of PANI-Au asymmetric composites and the fabrication process of the ECL immunosensor [80]. The image reproduced with the permission from Elsevier B.V. B) Synthetic route for dual dye-loaded SERS tags and schematic illustration of quantitative detection of human IgM using SERS-based lateral flow immunoassay [81]. The images reproduced with the permission from The Royal Society of Chemistry. C) Schematic representation of the Au-nanoprobe detection of the early RA biomarker-IgM RF, whose colorimetric output provides for the readout. On the right: actual photos of real detection samples to illustrate color discrimination by the naked eye [82]. The image reproduced with the permission from The Royal Society of Chemistry. D) Illustration of ADAMTS-4 detective fluorescent turn-on peptide-conjugated AuNP probe (ADAMTS-4-D-Au probe) for the Detection of ADAMTS-4. (i) Fluorescence images and intensity of the ADAMTS-4-D-Au probe in the presence of various concentrations of ADAMTS-4 to test sensitivity [83]. The images reproduced with the permission from American Chemical Society.