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. 2022 Dec 22;14:1068278. doi: 10.3389/fnagi.2022.1068278

Table 2.

Risk prediction models for postoperative delirium in geriatric patients with hip fractures.

Source Variables OR (95% CI) Scores AUC (95% CI)
Kim et al. (2020) Preoperative delirium 8.32 (6.78–10.21) 8 Derivation cohorts: 0.77 (0.76–0.78); Validation cohorts: 0.77 (0.75–0.79)
Preoperative dementia 2.38 (2.05–2.76) 3
Age
70–79 year 1.60 (1.20–2.12) 2
80–89 year 2.09 (1.59–2.74) 2
≥ 90 year 2.43 (1.82–3.23) 3
Medical co-management 1.43 (1.13–1.81) 1
ASA physical status III - V 1.40 (1.14–1.73) 1
Functional dependence 1.37 (1.17–1.61) 1
Smoking 1.36 (1.07–1.72) 1
SIRS/sepsis/septic shock 1.34 (1.09–1.65) 1
Preoperative use of mobility aid 1.32 (1.14–1.52) 1
Oberai et al. (2021) Age > 80 year 1.6 (1.4–1.9) 5 Derivation cohorts: 0.742; Validation cohorts: 0.746
Male gender 1.3 (1.1–1.5) 2
Mobilization opportunity 1.9 (1.4–2.6) 6
Surgery delay 1.7 (1.2–2.5) 6
Cognition not assessed 1.5 (1.3–1.9) 4
Cognition impaired 1.7 (1.3–2.1) 5
Prior impaired cognition or known dementia 3.90 (3.2–4.7) 14
Shen et al. (2022) Preoperative delirium 4.21 (3.25–9.14) 4 Derivation cohorts: 0.848 (0.72–0.90); Validation cohorts: 0.833 (0.68–0.89)
CVA with the modified Rankin scale
≥ 4 3.17 (1.16–5.06) 3
2–3 2.25 (1.26–4.29) 2
Diabetes with random glucose level
> 13 mmol/l 2.43 (1.32–2.99) 2
8–13 mmol/l 1.36 (1.15–1.67) 1
CCI score
≥ 9 2.32 (1.69–4.83) 2
6–8 1.29 (1.03–2.52) 1
Age
≥ 80 year 1.87 (1.25–2.50) 2
70–79 year 1.11 (1.07–2.19) 1
Application of Benzodiazepines in surgery 1.44 (1.24–3.17) 1
Surgical delay ≥ 2 days 1.15 (1.13–1.28) 1
Creatine ≥ 90 μmol/l 1.09 (1.02–1.13) 1
Active smoker 1.05 (1.04–1.94) 1

OR, odds ratio; CI, confidence interval; AUC, area under the curve; ASA, American Society of Anaesthesiologists; SIRS, systemic inflammatory response syndrome; CVA, cerebrovascular accident; CCI, Carlson comorbidity index.