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. 2022 Dec 26;56:101776. doi: 10.1016/j.eclinm.2022.101776

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© 2022 The Author(s)

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Fig. 1 — A: Diagram of PrEP regimens for a typical week: daily PrEP: one pill per day; on-demand PrEP: two pills 2–24 h before sex acts (only one pill if other pills taken in previous seven days), one pill 24 h after the last pre-sex pill, and one pill 24 h after that. B: Diagram of PrEP regimens' adherence interval types. Each regimen's adherence interval depended on previous pills taken (outlined label boxes) and on time before or after sex acts. Pill taking and sex acts here are to illustrate when each adherence interval occurs and do not reflect actual data.