Table 1.

Probability of pill taking within each adherence interval type.

	Interval type	Parameter	Pill taking probability: Harlem		Pill taking probability: Bangkok
			Median	IQR	Median	IQR
A. Daily PrEP	Pill taken day before	D1	79%	62–90%	93%	81–97%
	Pill not taken day before	D2	46%	28–65%	79%	53–92%
B. On-demand PrEP	No sex act day before, day of, day after	O1	7%	3–16%	7%	4–11%
	2–24 h prior to sex act	O2	29%	21–40%	36%	32–40%
	0–2 h prior to sex act, pill taken in 2–24 h window	O3	20%	12–30%	19%	13–27%
	0–2 h prior to sex act, pill not taken in 2–24 h window	O4	31%	15–53%	55%	45–65%
	Day 1 after sex act, pre-sex act pill taken	O5	18%	11–28%	43%	31–57%
	Day 1 after sex act, pre-sex act pill not taken	O6	13%	9–20%	6%	3–11%
	Day 2 after sex act, day 1 after sex act pill taken	O7	90%	NA	90%	NA
	Day 2 after sex act, day 1 after sex act pill not taken	O8	13%	9–20%	6%	3–11%

A: Probabilities of daily PrEP use estimated from daily HPTN 067 arm data. B: Probabilities of on-demand PrEP use based on probabilities estimated from event-driven HPTN 067 arm data, with the exception of the second post-sex act pill, which was assigned 90% probability based on 2-1-1 adherence data.¹¹