Figure 2.

Inferred HPTM associations and subject-wise variability in healthy subjects

(A and B) Acetylation and B) methylation panel HPTM networks inferred from task 3 (HPTMs → HPTM) NP models. Arrows go from input to output HPTM.

(C) Comparison of inferred association strengths from NP and kNN models. Each dot represents the association strength of a pair of HPTMs in the association networks from the corresponding models. Wilcoxon test was used to compute the significance in the difference of means (n = 27, 28 HPTM associations for kNN, NP respectively).

(D) Summary of variation in model association strength across subjects. Each dot represents a model. Association strength of a model is the strength of all associations containing input and output of the model.

See also Figures S3–S6.