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. 2022 Dec 17;18:100524. doi: 10.1016/j.mtbio.2022.100524

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© 2022 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

PMC Copyright notice

Fig. 14 — Schematic illustration of dendrimers structure and their drug delivery for SCI treatment. (A) Chemical structure of PAMAM (G2) and its two drug-loaded forms (incorporation in the bulk and bonding to functional groups). Copyright 2008 Journal of Controlled Release [112], 2010 Progress in Polymer Science [113]. (B) The preparation of MP loaded CMCht/PAMAM dendrimer NPs and local injections for SCI treatment. Fluorescence image showed the internalization of the NPs at the lesion site. Copyright 2013, Small [114].