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. Author manuscript; available in PMC: 2023 May 1.
Published in final edited form as: Obesity (Silver Spring). 2022 May;30(5):1039–1056. doi: 10.1002/oby.23412

Table 3.

Weight, BMI, body composition, and cardiorespiratory fitness by intervention condition.

Least-Squares Mean (95% CI)* P value P value for Pairwise Comparisons of Change
at 6 Months****
P value for Pairwise Comparisons of Change
at 12 Months****
Baseline Change from
Baseline to
6 months
Change from
Baseline to
12 months
Group Time** Group x
Time
DIET
vs.
DIET+MODPA
DIET
vs.
DIET+HIGHPA
DIET+MODPA
vs.
DIET+HIGHPA
DIET
vs.
DIET+MODPA
DIET
vs.
DIET+HIGHPA
DIET+MODPA
vs.
DIET+HIGHPA
Weight, kg N = 383 N = 340 N = 322 0.5684 0.0152 0.2979 0.1643 0.2532 0.8017 0.4503 0.9928 0.4477
 DIET 91.8 (90.0, 93.6) −8.5 (9.5, −7.5)*** −9.4 (−10.8, −8.0)***
 DIET+MODPA 89.9 (88.3, 91.6) −9.5 (−10.5, −8.5)*** −10.1 (−11.5, −8.8)***
 DIET+HIGHPA 91.0 (89.4, 92.6) −9.3 (−10.3, −8.3)*** −9.4 (−10.8, −8.0)***
Weight change from baseline, % N = 340 N = 322 0.6010 0.0175 0.2763 0.1843 0.1843 0.9931 0.4902 0.9182 0.5591
 DIET −---- −9.3 (−10.3, −8.2)*** −10.2 (−11.7, −8.8)***
 DIET+MODPA −---- −10.3 (−11.4, −9.2)*** −11.0 (−12.4, −9.5)***
 DIET+HIGHPA −---- −10.3 (−11.3, −9.2)*** −10.3 (−11.8, −8.9)***
Body Mass Index, kg/m2 N = 383 N = 340 N = 322 0.4985 0.0133 0.3342 0.1275 0.1948 0.8198 0.3929 0.8985 0.4702
 DIET 32.6 (32.0, 33.2) −3.0 (−3.3, −2.6)*** −3.3 (−3.8, −2.8)***
 DIET+MODPA 32.3 (31.6, 32.9) −3.4 (−3.7, −3.0)*** −3.6 (−4.1, −3.1)***
 DIET+HIGHPA 32.2 (31.5, 32.9) −3.3 (−3.6, −3.0)*** −3.3 (−3.8, −2.8)***
Fat mass (kg) N = 383 N = 339 N = 316 0.5348 0.0076 0.4961 0.1164 0.1467 0.9056 0.5206 0.7303 0.7688
 DIET 39.3 (38.4, 40.2) −7.0 (−7.8, −6.2)*** −7.8 (−8.9, −6.6)***
 DIET+MODPA 38.6 (37.6, 39.6) −7.9 (−8.7, −7.1)*** −8.3 (−9.5, −7.2)***
 DIET+HIGHPA 39.6 (38.5, 40.8) −7.8 (−8.6, −7.0)*** −8.1 (−9.2, −6.9)***
Lean mass (kg) N = 383 N = 339 N = 316 0.5501 0.8615 0.6134 0.7688 0.8999 0.6063 0.3502 0.7478 0.2134
 DIET 49.3 (48.1, 50.5) −1.4 (−1.7, −1.1)*** −1.4 (−1.7, −1.1)***
 DIET+MODPA 48.2 (47.2, 49.2) −1.5 (−1.8, −1.2)*** −1.6 (−2.0, −1.3)***
 DIET+HIGHPA 48.3 (47.3, 49.3) −1.4 (−1.7, −1.1)*** −1.3 (−1.7, −1.0)***
Percent body fat (%) N = 383 N = 339 N = 316 0.5868 0.0004 0.3299 0.1384 0.0934 0.8450 0.6492 0.7967 0.8458
 DIET 43.1 (42.5, 43.7) −4.2 (−4.8, −3.7)*** −5.1 (−5.9, −4.2)***
 DIET+MODPA 42.6 (41.8, 43.4) −4.8 (−5.4, −4.3)*** −5.3 (−6.2, −4.5)***
 DIET+HIGHPA 43.5 (42.7, 44.2) −4.9 (−5.5, −4.4)*** −5.2 (−6.1, −4.4)***
Cardiorespiratory Fitness (ml/kg/min) N = 381 N = 331 N = 309 0.0081 0.4946 0.0612 0.0888 0.0008 0.0943 0.0120 0.0476 0.5958
 DIET 23.1 (22.5, 23.6) 2.0 (1.4, 2.5)*** 2.1 (1.4, 2.9)***
 DIET+MODPA 22.3 (21.7, 22.9) 2.7 (2.1, 3.2)*** 3.3 (2.6, 3.7)***
 DIET+HIGHPA 22.6 (22.0, 23.1) 3.4 (2.8, 3.9)*** 3.0 (2.3, 3.7)***
Cardiorespiratory Fitness (L/min) N = 381 N = 331 N = 309 0.0435 0.1680 0.1228 0.4208 0.0141 0.0983 0.0330 0.0597 0.7983
 DIET 2.1 (2.1, 2.2) −0.03 (−0.08, 0.01) −0.06 (−0.11, −0.01)***
 DIET+MODPA 2.0 (1.9, 2.1) −0.01 (−0.05, 0.04) 0.01 (−0.04, 0.06)
 DIET+HIGHPA 2.0 (2.0, 2.1) 0.05 (0.00, 0.09) 0.00 (−0.04, 0.05)
Cardiorespiratory Fitness (termination time, minutes) N = 383 N = 337 N = 312 0.0285 0.1598 0.5206 0.1630 0.0092 0.2306 0.0638 0.0631 0.09957
 DIET 7.8 (7.5, 8.2) 1.6 (1.2, 2.1)*** 1.5 (1.0, 1.9)***
 DIET+MODPA 7.5 (7.1, 7.9) 2.1 (1.6, 2.5)*** 2.1 (1.6, 2.5)***
 DIET+HIGHPA 7.9 (7.5, 8.2) 2.4 (2.0, 2.8)*** 2.1 (1.6, 2.5)***
*

Model adjusted for sex and race and baseline value.

**

P-value for comparison of change at 6 months to change at 12 months.

***

Indicates change from baseline is statistically significant at p-value ≤0.0167 to adjust for multiple comparisons.

****

P-value for comparison of groups at specific time points, with the critical p-value set at ≤0.0167 to adjust for multiple comparisons.