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. Author manuscript; available in PMC: 2024 Jan 1.
Published in final edited form as: Am J Sports Med. 2022 Dec 7;51(1):81–96. doi: 10.1177/03635465221135769

Figure 2. ACL injury decreases translational signaling in human quadriceps skeletal muscle.

Figure 2.

Human quadriceps muscle protein lysates were probed with (A) phospho-AKTSer473, (B) total AKT, (C) phospho/total AKT, (D) phospho-RPS6Ser235/236, (E) total RPS6, (F) phospho/total RPS6, (G) phospho eIF2αSer51, and (H) total eIF2α, and (I) phospho/total eIFα. ** P < .01 vs Healthy limb, *** P <.005 vs Healthy limb, **** P < .0001 vs Healthy limb via paired t-tests. Values are presented as mean ± SD with individual data points overlaid. n=21 subjects in panels A-F and n=14 subjects in panels G-I. “+” denotes ACL injured limb, “-“ denotes healthy contralateral limb.