Figure 9. Quadriceps gene expression changes in human whole muscle and murine myonuclei in response to ACL injury.
Over-representation and under-representation analysis of pathways with up-regulated and down-regulated genes following ACL injury in (A) human quadriceps and (B) murine quadriceps myonuclei. Blue bars = up-regulated pathways, red bars = down-regulated pathways. (A) n=16 human subjects; (B) n=3 pooled biological replicates of murine quadriceps myonuclei. Dashed line represents FDR adjusted P < .05.