Table 1.
Characteristics of atrial fibrillation (Af) patients aged ≥ 65 years (2015).
| Variable | All | VKA | DOAC | None | ||||
|---|---|---|---|---|---|---|---|---|
| (n = 12,076) | (n = 2991) | (n = 3770) | (n = 5315) | |||||
| Age (years) mean (SD) | 78.8 | (7.7) | 79.1 | (7.6) | 77.9 | (7.3) | 79.2 | (8.1) |
| Female n (%) | 2724 | (41) | 1184 | (40) | 1559 | (41) | 2447 | (46) |
| CHADS2 score mean (SD) | 2.5 | (1.4) | 3.0 | (1.3) | 2.7 | (1.3) | 2.1 | (1.3) |
| CHA2DS2-VASc score mean (SD) | 4.1 | (1.5) | 4.5 | (1.4) | 4.2 | (1.5) | 3.7 | (1.5) |
| HAS-BLED score mean (SD) | 2.6 | (1.1) | 2.9 | (1.0) | 2.7 | (1.0) | 2.3 | (1.1) |
| Comorbidities n (%) | ||||||||
| Cerebral infarction/TIA | 2995 | (25) | 832 | (28) | 977 | (26) | 1164 | (22) |
| Heart failure | 6411 | (53) | 1931 | (65) | 1997 | (53) | 2447 | (46) |
| Vascular disease | 1609 | (13) | 431 | (14) | 461 | (12) | 709 | (13) |
| Chronic kidney disease | 1342 | (11) | 422 | (14) | 292 | (8) | 622 | (12) |
| Liver damage | 2403 | (20) | 599 | (20) | 711 | (19) | 1079 | (20) |
| Bleeding | 2727 | (23) | 773 | (26) | 760 | (20) | 1183 | (22) |
| Alcoholism | 147 | (1.2) | 40 | (1.3) | 47 | (1.2) | 59 | (1.1) |
| Hypertension | 7910 | (65) | 2583 | (86) | 3051 | (81) | 2226 | (42) |
| Diabetes mellitus | 1723 | (14) | 545 | (18) | 702 | (19) | 467 | (9) |
| Dialysis | 142 | (1.2) | 46 | (1.5) | 1 | (0.0) | 95 | (1.8) |
| Concomitant drugs n (%) | ||||||||
| Antiplatelet drugs | 702 | (5.8) | 174 | (5.8) | 195 | (5.2) | 327 | (6.2) |
| NSAIDs | 2005 | (17) | 584 | (18) | 679 | (18) | 762 | (14) |
*CHADS2 score heart failure, hypertension, age ≥ 75 years, diabetes mellitus, prior cerebral infarction, or TIA(doubled).
†CHA2DS2-VASc score heart failure, hypertension, age ≥ 75 years (doubled), diabetes mellitus, prior cerebral infarction or TIA (doubled), vascular disease, age 65–74 years, female sex.
‡HAS-BLED score hypertension, renal and hepatic dysfunction, stroke, bleeding, age ≥ 65 years, concomitant antiplatelet drugs and NSAIDs, alcoholism.
§TIA transient ischemic attack.
IINSAIDs non-steroidal anti-inflammatory drugs.