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. 2023 Jan 5;23:2. doi: 10.1186/s12893-022-01891-7

Table 1.

Basic data of the included studies

Author and Publication year	Country	Study design	Study period	Arm	Sample size (n)	Age (yr)	Gender: M/F(n)	Child score(A/B/C)	Virology (HBV/HCV/Both)	Cirrhosis (n/%)	ICG-R15 (%)	Tumor size (cm)	Tumor number (S/M)	Vascular invasion (%)	Resection margin (< 1 cm/ > 1 cm)
Wu, 1999 [15]	Taiwan	Retrospective Cohort	1987–1997	CH	15	53.0 ± 11.6 ^a	15/0	14/1/0	13/2/0	11–	N/A	12.8	N/A	N/A	N/A
Wu, 1999 [15]	Taiwan	Retrospective Cohort	1987–1997	EH	25	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Hu, 2003 [12]	Taiwan	Cohort	1993–1999	CH	52	N/A	N/A	N/A	24(HCV)	24	17.4 ± 1.5^a	< 9	47/5	12	22/30
Hu, 2003 [12]	Taiwan	Cohort	1993–1999	EH	63	N/A	N/A	N/A	13(HCV)	24	12.4 ± 2.2^a	< 9	50/13	26	16/47
Cheng, 2012 [16]	Taiwan	Cohort	1999–2005	CH	63	58(50–66)^b	50/13	56/7/0	43/13/0	30 (47.6%)	8.57 (5.20–13.53)^b	6.50 (5.50–8.50)^b	N/A	30 (47.6%)	50//4
Cheng, 2012 [16]	Taiwan	Cohort	1999–2005	EH	41	61(50–68.5)^b	32/9	37/3/0	27/8/0	15 (36.6%)	8.14 (5.88–14.48)^b	8.00 (5.50–10.25)^b	N/A	19 (46.3%)	30//8
Chen, 2014 [17]	China	Cohort	2002–2008	CH	118	56.4 ± 12.3^a	96/22	6.7 ± 1.2	100/15/0	106	5.3 ± 2.0	8.6 ± 2.4	N/A	30	39/79
Chen, 2014 [17]	China	Cohort	2002–2008	EH	80	N/A	67/13	N/A	69/10/0	68	N/A	N/A	N/A	24	13/67
Yang, 2014 [18]	China	Retrospective Cohort	2002–2012	CH	350	N/A	298/52	298/52/0	315 (HBV)	281	N/A	N/A	161/189	195	144/206
Yang, 2014 [18]	China	Retrospective Cohort	2002–2012	EH	346	47.5 ± 11.8^a	289/57	284/62/0	303 (HBV)	272	N/A	8.1 ± 5.3^a	141/205	194	133/213
Chinburen, 2015 [19]	Mongolia	Retrospective Cohort	2003–2012	CH	45	59.8 ± 8.5^a	23/22	30/0/0	14/21/0	N/A	N/A	5.9 ± 2.2^a	37/8	N/A	N/A
Chinburen, 2015 [19]	Mongolia	Retrospective Cohort	2003–2012	EH	24	55.4 ± 9.2 ^a	12//12	14/1/0	8/7//0	N/A	N/A	7.2 ± 2.1 ^a	21/3	N/A	N/A
Chen, 2017 [20]	Taiwan	Retrospective Cohort	2007–2010	CH	15	62 ± 14^a	12//3	N/A	10/3//1	3	8.94 ± 5.08^a	4.71 ± 2.25^a	N/A	5	N/A
Chen, 2017 [20]	Taiwan	Retrospective Cohort	2007–2010	MH	33	60 ± 13^a	22/11	N/A	18//5//2	15	8.34 ± 4.31^a	5.28 ± 4.17^a	N/A	15	N/A
Li, 2018 [13]	China	Retrospective Cohort	200–2016	CH	87	53.0 ± 7.8^a	63/24	N/A	74 (HBV)	80	7.3 ± 1.9^a	4.2 ± 0.9^a	N/A	10 (11.5%)	N/A
Li, 2018 [13]	China	Retrospective Cohort	200–2016	MH	84	54.4 ± 9.2^a	66/18	N/A	70 (HBV)	67	7.3 ± 2.3^a	4.1 ± 1.0 ^a	N/A	10 (11.9%)	N/A
Orimo, 2021 [21]	Japan	Retrospective Cohort	200–2019	CH	132	68 (39–86)^b	112/20	N/A	40/39/0	N/A	11.6 (2.9–86.7)^b	4.5 (1.2–15.2)^b	91/41	N/A	N/A
Orimo, 2021 [21]	Japan	Retrospective Cohort	200–2019	MH	101	65 (33–85) ^b	85/16	N/A	45/22/0	N/A	10.8 (1.4–54.0)^b	6.5 (0.6–22.5) ^b	65/36	N/A	N/A

^aThe results are presented as means and standard deviation

^bThe results are presented as median and range