Table 2. Quality assessment of randomized control trials using Cochrane bias tool.

Article	Random sequence generation –Selection Bias	Allocation of concealment – Selection bias	Blinding of both participants and evaluators – Performance Bias	Blinding of assessment during outcome collection – Detection bias	Incomplete outcome data – Attrition Bias	Selective reporting – Reporting Bias	Other bias/ Comments
Liem et al. 2019[16]	Low risk	Low risk	High risk	Low risk	Low risk	Low risk	Due to the intervention, patients, clinicians, and the study team could not be blinded to treatment allocation.
Suárez et al. 2018[17]	Low risk	Low risk	High risk	Low risk	Low risk	Low risk
Huang et al. 2021 [18]	Low risk	Low risk	High risk	Low risk	Low risk	Low risk
Ahn et al. 2021[19]	Low risk	Low risk	High risk	Low risk	Low risk	Low risk
Hsu et al. 2018[20]	Low risk	Low risk	High risk	Low risk	Low risk	Low risk
Jeng et al. 2019 [21]	Low risk	Low risk	High risk	Low risk	Low risk	Low risk
Kranidioti et al.2019[22]	Low risk	Low risk	High risk	Low risk	Low risk	Low risk
Li et al. 2021[23]	Low risk	Low risk	High risk	Low risk	Low risk	Low risk
Manolakopoulos et al. 2020[24]	Low risk	Low risk	High risk	Low risk	Low risk	Low risk