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. 2001 Apr;69(4):2162–2171. doi: 10.1128/IAI.69.4.2162-2171.2001

FIG. 7.

FIG. 7

Protozoal DNA stimulates NO production. Macrophages were cultured with the indicated DNA, IFN-γ, and polymyxin B sulfate for 48 h, and supernatants were assayed for NO2− production by the Griess assay. Results are presented as the mean and 1 SD of triplicate determinations. (A to C) Significantly more NO2− was induced by parasite or E. coli DNA than no DNA (none) or bovine DNA (P < 0.02, indicated by asterisk). (B) Significantly more NO2− was induced by untreated T. brucei DNA than by the corresponding methylated DNA (P < 0.01, indicated by octothrop).