Table 3.
Characteristic of 1108 NSCLC patients with ICI from Nanfang Hospital cohort
| Variables | ICI-combined therapy, N = 956(%) | ICI monotherapy, N = 152(%) | P-value |
|---|---|---|---|
| Age | 61.4 | 61.5 | |
| Sex | 0.67 | ||
| Female | 239 (25.0) | 41 (27.0) | |
| Male | 717 (75.0) | 111 (73.0) | |
| Clinical Stage (AJCC 8th edition) | 0.002 | ||
| I–III | 274 (28.7) | 25 (16.4) | |
| IV | 682 (71.3) | 127 (83.6) | |
| Smoking status | 0.220 | ||
| Ever smoking | 590 (61.7) | 84 (55.3) | |
| Never smoking | 315 (33.0) | 61 (40.1) | |
| Unknown | 51 (5.3) | 7 (4.6) | |
| Pathology subtypes | 0.725 | ||
| Squamous cell carcinoma | 337 (35.3) | 50 (32.9) | |
| Adenocarcinoma | 506 (52.9) | 81 (53.3) | |
| Others | 113 (11.8) | 21 (13.8) | |
| IP | 0.065 | ||
| With IP | 75 (7.8) | 5 (3.3) | |
| Without IP | 881 (92.2) | 147 (96.7) |
IP Interstitial pneumonitis
P < 0.05 indicates a significant difference