Table 2.
AUCs of GFAP and PreSS for identification of stroke, ICrH, and LVO
| GFAP | PreSS part 1 | PreSS part 2 | GFAP and PreSSa | |||||
|---|---|---|---|---|---|---|---|---|
| Apparent AUC | Cross fold validated AUC | Apparent AUC | Cross fold validated AUC | Apparent AUC | Cross fold validated AUC | Apparent AUC | Cross fold validated AUC | |
| Stroke and TIA | 0.62 (0.56–0.69) | 0.54 (0.47–0.60) | 0.66 (0.60–0.72) | 0.64 (0.58–0.71) | n/a | n/a | 0.65 (0.58–0.71) | 0.65 (0.59–0.71) |
| ICrH | 0.79 (0.69–0.89) | 0.73 (0.62–0.84) | 0.71 (0.61–0.81) | 0.69 (0.58–0.80) | 0.71 (0.62–0.81) | 0.66 (0.57–0.79) | 0.80 (0.71–0.90) | 0.71 (0.59–0.83) |
| LVO | 0.44 (0.32–0.55) | 0.35 (0.23–0.46) | 0.76 (0.66–0.85) | 0.72 (0.62–0.82) | 0.69 (0.58–0.81) | 0.66 (0.54–0.78) | 0.71 (0.60–0.82) | 0.67 (0.55–0.79) |
AUC area under the receiver-operating characteristics curve, GFAP glial fibrillary acidic protein, ICrH intracranial hemorrhage, LVO large-vessel occlusion, PreSS Prehospital Stroke Score, TIA transient ischemic attack
aGFAP combined with: PreSS part 1 to identify stroke and TIA; PreSS part 1 and 2 to identify ICrH; and PreSS part 2 to identify LVO
Numbers in parentheses = 95% confidence interval