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. 2022 Nov 1;128(1):148–159. doi: 10.1038/s41416-022-02032-w

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Fig. 3 — a, b Phosphorylation of serine 298, but not serine 217, on MEK upregulated in sotorasib-resistant cells. c, d Phosphorylation of PAK proteins upregulated in sotorasib-resistant cells. e, f Enhanced phosphorylation of serine 338 of CRAF was observed in sotorasib-resistant cells. g, h Western blotting showed increased Src phosphorylation in sotorasib-resistant cells. i, j Treatment with dasatinib reduced the phosphorylation of PAKs and MEK1 on S298.