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. 2022 Nov 3;5:143. doi: 10.1038/s42004-022-00761-w

Fig. 1. Conceptualization of the phosphorylation with H3PO3 in liquid SO2.

Fig. 1

Condensation of a substrate with H3PO3 in liquid SO2 at room temperature yields the corresponding H-phosphonate. Under the same reaction conditions the reaction medium oxidizes the H-phosphonate intermediate to the phosphate analogue.