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. 2021 Jun 23;4:95. doi: 10.1038/s42004-021-00536-9

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — Technical drawings of the CFP (A) and zoomed section of the T-valve indicating inner (orange arrow) and outer (cyan arrows) flow directions (B), dynamic sealing (C), and sample threaded vial (D). Numbers indicate the most important components of the device: quick release connection (1), T-valve (2), one-way valve (3), dynamic sealing (4), vial top part (5), vial bottom part (6), outer-lumen to inner-lumen transition (7), black PEEK outer-lumen (8), red PEEK inner-lumen (9), dynamic sealing silicon O-ring (10), laser-welded joint (11), vial PTFE O-ring (12), nozzle (13).